With the Chiefs' defense being one of the best against the run, allowing just 83.2 yards per game on the ground, the third-fewest in the league, the Bills will likely take to the air early and often.
The Kansas City Chiefs will have some tough decisions to make if they want to keep their offensive line intact.
Trading Erik Karlsson might not be impossible, but the veteran defenseman ultimately has the final say as for whether he stays with the Penguins.