SCOTT CITY, Mo. (WSIL) -- A Cape Girardeau man was seriously injured after a single-vehicle crash in Scott County on Saturday ...

A man is dead after police said he was hit by a semi-truck in the roadway, minutes after he was involved in a separate crash.

A man is dead after police said he was hit by a semi-truck in the roadway, minutes after he was involved in a separate crash.

CARTERVILLE Ill. (WSIL) -- It'll be a cool start to our weekend, with low temperatures dropping into the upper 30s Saturday ...

The United States’ first known case of a more severe strain of mpox was confirmed in California, the US Centers for Disease Control and Prevention said Saturday. The ...

A massive, multi-story building in the Washington, DC, neighborhood of Georgetown welcomed back a former occupant this month that had been gone for over a decade.

YouTuber-turned-boxer Jake Paul defeated former heavyweight champion Mike Tyson via unanimous decision in their highly ...

President-elect Donald Trump promised Americans he’d bring down consumer prices, make health care more affordable and protect ...

It’s called sticker shock. And if you haven’t been to a dealer’s showroom since before the pandemic, you might want to prepare yourself.

Authorities are urging motorists to avoid the area and take a different route of travel due to a crash on I-57 on Friday.

HERRIN, Ill. (WSIL) -- A 46-year-old man faces multiple charges after he is accused of domestic battery and arson in Herrin.

Despite decades of calls for more attention to patient safety in hospitals, people undergoing surgery still have high rates ...